What is C02 laser therapy? The CO2 laser is a carbon dioxide laser used to resurface skin and treat wrinkles, uneven skin coloration, acne scarring and other skin concerns. The results are similar to those of chemical peels and dermabrasion, except that the laser removes skin layers by vaporization rather than with chemicals or a sanding device and the results tend to be much more dramatic. Laser therapy can only be preformed by a registered nurse in California, but in some states, a licensed esthetician can do them. From what I’ve read, the service costs $2,600 on average, but would have been around $2,000 where I got mine done.